Reference: Sperm count is increased by diet-induced weight loss and maintained by exercise or GLP-1 analogue treatment: a randomized controlled trial Human Reproduction, deac096, https://doi.org/10.1093/humrep/deac096
其實植物跟中藥當中很多都包含黃體素,像是聖潔梅、桑寄生、菟絲子、肉桂、續斷等等,但我們並不是以黃體素不足來看,臨床上黃體不足常與腎陽腎氣不足相關,但並不是光開立補充腎陽中藥而已,而是綜合舌脈、整體、基礎體溫來辨證開藥。 此外臨床上常用固胎、安胎的藥物在中藥中也有許多機轉臨床常見用以安胎之中藥,包括清熱類的黃芩、健脾類的白朮、補血類的阿膠、補肝腎類的續斷、菟絲子、桑寄生、杜仲等。其安胎機轉包括:增加黃體素含量、抑制子宮平滑肌收縮、清除自由基、抗氧化、抑制母體對胚胎的免疫排斥、強化造血機能、抑制子宮出血、預防妊娠高血壓、增加鋅含量、促進葉酸吸收與代謝、增加維生素 E 含量等。
謝宜庭中醫師 繪圖
Reference:
臨床常用安胎中藥機轉與安全性探討 王隆碩 陳豪君 李俊廷 中醫藥研究論叢, 17(1), 2014 Taipei Journal of Traditional Chinese Medicine, 17(1), 201
Micronized vaginal progesterone to prevent miscarriage: a critical evaluation of randomized evidence AUGUST 2020 American Journal of Obstetrics & Gynecology
Key to Life: Physiological Role and Clinical Implications of Progesterone Int. J. Mol. Sci. 2021, 22, 11039
The Effect of Acupressure on the Severity of Nausea, Vomiting, and Retching in Pregnant Women: A Randomized Controlled Trial Complement Med Res Tara et al. DOI: 10.1159/000505637
Manual Acupuncture Reduces Hyperemesis Gravidarum: A Placebo-Controlled, Randomized, Single-Blind, Crossover Study Journal of Pain and Symptom Management Vol. 20 No. 4 October 2000
1. Liraglutide increases IVF pregnancy rates in obese PCOS women with poor response to first-line reproductive treatments: a pilot randomized study, 2018 European Society of Endocrinology
2. Polycystic ovarian syndrome and infertility: overview and insights of the putative treatments, GYNECOLOGICAL ENDOCRINOLOGY 2021, VOL. 37, NO. 10, 869–874
3. A brief update on the evidence supporting the treatment of infertility in polycystic ovary syndrome, Aust N Z J Obstet Gynaecol 2019; 59: 867–873
4. Generational Health Impact of PCOS on Women and Their Children
Med. Sci. 2019, 7, 49; doi:10.3390/medsci7030049
5. PCOS and pregnancy: a review of available therapies to improve the outcome of pregnancy in women with polycystic ovary syndrome EXPERT REVIEW OF ENDOCRINOLOGY & METABOLISM, 2018
6. Association of Metformin With Pregnancy Outcomes in WomenWith Polycystic Ovarian Syndrome Undergoing In Vitro Fertilization JAMA Network Open. 2020;3(8):e2011995. doi:10.1001/jamanetworkopen.2020.11995